Description

3-Chlorobenzo[B]Thiophene-2-Carbonyl Chloride is a high-purity, reactive organic intermediate featuring both an acid chloride and a chlorinated benzothiophene moiety. This compound is critical for the synthesis of complex molecules, particularly in pharmaceutical and advanced material research, where it serves as a versatile building block. It is primarily sought by R&D chemists and process development scientists in the agrochemical, pharmaceutical, and specialty chemical industries for constructing novel heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory pathways.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides with specific modes of action.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of organic semiconductors and conductive polymers.
• Ligand and Catalyst Development: Employed to create sophisticated ligands for transition metal catalysis and organocatalysts.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized chromophores and high-performance pigments.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom chemical synthesis services catering to advanced R&D projects.

Basic Information

Product Name	3-Chlorobenzo[B]Thiophene-2-Carbonyl Chloride
CAS No.	21815-91-8
Molecular Formula	C9H4Cl2OS
Molecular Weight	231.10 g/mol
Synonyms	3-Chlorobenzo[b]thiophene-2-carbonyl chloride; 3-Chloro-2-benzothiophenecarbonyl chloride; 3-Chloro-1-benzothiophene-2-carbonyl chloride; 2-Benzothiophenecarbonyl chloride, 3-chloro-; 3-Chlorothianaphthene-2-carbonyl chloride; 3-Chloro-benzo[b]thiophene-2-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 3-Chlorobenzo[B]Thiophene-2-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, GC, NMR, and FTIR to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical parameters. Our commitment to quality supports compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases, oxidizing agents, and sources of moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.