Description

(3R)-3,4,5,6,6Aα,7,8,9-Octahydro-2,2,6α,9β-Tetramethyl-3,9Aβ-Methano-2H-Cyclopent[B]Oxocin-5α-Ol is a high-purity, complex polycyclic alcohol of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical chiral building block and intermediate for developing novel active pharmaceutical ingredients (APIs) and fine chemicals. It is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to leverage its unique stereochemistry and functional group array.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, particularly in steroid-like or terpenoid-based therapeutic areas.
• Advanced Organic Synthesis: Used as a sophisticated building block in total synthesis projects, enabling the construction of intricate natural product analogs.
• Agrochemical Research: Serves as a precursor in the development of new, high-efficacy crop protection agents with specific biological activity.
• Fragrance & Flavor Chemistry: Potential intermediate for creating novel, high-value aroma chemicals due to its complex polycyclic structure.
• Material Science Research: Investigated as a monomer or functional additive for specialty polymers with tailored properties.
• Catalysis & Ligand Development: Can be utilized to develop novel chiral ligands or organocatalysts for asymmetric synthesis.

Basic Information

Item	Details
Product Name	(3R)-3,4,5,6,6Aα,7,8,9-Octahydro-2,2,6α,9β-Tetramethyl-3,9Aβ-Methano-2H-Cyclopent[B]Oxocin-5α-Ol
CAS No.	21764-23-8
Molecular Formula	C₁₇H₂₈O₂
Molecular Weight	264.40 g/mol
Synonyms	5α-Hydroxy-2,2,6α,9β-tetramethyl-3,9aβ-methano-2H-cyclopent[b]oxocin; (3R,5α,6α,9α,9aβ)-3,4,5,6,6a,7,8,9-Octahydro-2,2,6α,9β-tetramethyl-3,9a-methano-2H-cyclopent[b]oxocin-5-ol; Ambroxol Impurity; Ambroxol Related Compound; Ambroxol EP Impurity; Ambroxol USP Impurity; trans-(-)-Ambroxol Intermediate
EINECS	Contact for details

Quality Control

Our (3R)-3,4,5,6,6Aα,7,8,9-Octahydro-2,2,6α,9β-Tetramethyl-3,9Aβ-Methano-2H-Cyclopent[B]Oxocin-5α-Ol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the stringent requirements for pharmaceutical impurity reference standards and advanced synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and compliance with relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.