Description

(1R)-2,3,3Aα,7,8,8Aα-Hexahydro-1α-Hydroxy-1,4-Dimethyl-7-(1-Methylethylidene)Azulen-6(1H)-One is a high-purity, complex sesquiterpenoid derivative with a defined stereochemistry, valued for its role as a key synthetic intermediate and building block in advanced organic synthesis. Its precise molecular architecture makes it a critical component for researchers and manufacturers developing novel compounds in the life sciences. This product is essential for B2B clients in the pharmaceutical, agrochemical, and fine chemical sectors who require reliable access to structurally defined, high-quality intermediates for process development and scale-up.

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex terpenoid or azulene-based structures.
• Agrochemical Research: Used in the development of new crop protection agents and pesticides, where its unique carbon skeleton can impart specific biological activity.
• Fine Chemical Synthesis: Acts as a starting material or intermediate for synthesizing specialty chemicals, flavors, fragrances, and advanced materials.
• Academic & R&D Laboratories: Employed in methodological studies, catalysis research, and the exploration of new synthetic pathways due to its stereochemical complexity.
• Process Chemistry & Scale-Up: Supplied to support route scouting, optimization, and pilot-scale production for new chemical entities.

Basic Information

Item	Detail
Product Name	(1R)-2,3,3Aα,7,8,8Aα-Hexahydro-1α-Hydroxy-1,4-Dimethyl-7-(1-Methylethylidene)Azulen-6(1H)-One
CAS No.	21698-40-8
Molecular Formula	C15H22O2
Molecular Weight	234.33 g/mol
Synonyms	(1R)-1-Hydroxy-1,4-dimethyl-7-(propan-2-ylidene)-2,3,3a,7,8,8a-hexahydroazulen-6-one; (-)-Guai-1(10),11-dien-9-one; 1α-Hydroxy-4α-methyl-7-isopropylidene-1,2,3,4,4aβ,5,6,8aβ-octahydroazulen-6-one; (1R,3aS,4S,8aS)-1-Hydroxy-1,4-dimethyl-7-(propan-2-ylidene)-2,3,3a,4,7,8-hexahydro-1H-cyclopenta[1,3]cyclopropa[1,2]benzene-6(8aH)-one; Guaiene derivative sesquiterpenoid
EINECS	Contact for details

Quality Control

Our (1R)-2,3,3Aα,7,8,8Aα-Hexahydro-1α-Hydroxy-1,4-Dimethyl-7-(1-Methylethylidene)Azulen-6(1H)-One is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and identity confirmation via IR and NMR. Certificates of Analysis (COA) documenting all specifications are provided to ensure traceability and compliance with your internal quality standards and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider inert gas purging to maintain product stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.