Description

(3Ar)-3A,4,4Aα,5,6,7,7Aα,9Aα-Octahydro-5α-Hydroxy-5,8-Dimethyl-3-Methyleneazuleno[6,5-B]Furan-2(3H)-One is a complex sesquiterpene lactone derivative, a class of compounds known for their significant biological activity. This high-purity intermediate is critical for advanced pharmaceutical research and synthesis, offering a structurally defined scaffold for drug discovery. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of potential therapeutic agents, particularly in anti-inflammatory and anticancer research.
• Medicinal Chemistry Research: Used as a core structure for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Natural Product Synthesis: Acts as a synthetic target or intermediate in the total synthesis of complex natural products with sesquiterpene skeletons.
• Biochemical Research: Employed as a reference standard or probe in studies investigating biological pathways and enzyme interactions.
• Fine Chemical Synthesis: Utilized in the multi-step synthesis of specialty chemicals and advanced materials requiring specific stereochemistry.

Basic Information

Product Name	(3Ar)-3A,4,4Aα,5,6,7,7Aα,9Aα-Octahydro-5α-Hydroxy-5,8-Dimethyl-3-Methyleneazuleno[6,5-B]Furan-2(3H)-One
CAS No.	21688-81-3
Molecular Formula	C₁₅H₂₀O₃
Molecular Weight	248.32 g/mol
Synonyms	5α-Hydroxy-5,8-dimethyl-3-methylidene-3a,4,4aα,5,6,7,7aα,9aα-octahydroazuleno[6,5-b]furan-2-one; 3-Methyleneazuleno[6,5-b]furan-2(3H)-one derivative; Sesquiterpene lactone intermediate; Azulenofuranone; Contact for additional trade names and abbreviations.
EINECS	Contact for details

Quality Control

Every batch of (3Ar)-3A,4,4Aα,5,6,7,7Aα,9Aα-Octahydro-5α-Hydroxy-5,8-Dimethyl-3-Methyleneazuleno[6,5-B]Furan-2(3H)-One is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency that meet the exacting standards for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.