Description

2,6-Dimethylphenylmagnesium Bromide is a highly reactive organometallic reagent, specifically a Grignard reagent, widely used in organic synthesis. Its primary value lies in its ability to act as a powerful nucleophile and strong base for the formation of carbon-carbon bonds, enabling the construction of complex molecular architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries who require precise and efficient synthetic methodologies.

Application

• As a key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug intermediates.
• For the preparation of liquid crystals and organic electronic materials used in display technologies.
• In the production of specialized ligands and catalysts for asymmetric synthesis and polymerization processes.
• As a reagent in fine chemical and agrochemical research for creating novel compounds with specific biological activities.
• For the functionalization of aromatic systems and the introduction of the 2,6-dimethylphenyl group into target molecules.
• In academic and industrial R&D laboratories for methodological studies in organometallic chemistry.

Basic Information

Product Name	2,6-Dimethylphenylmagnesium Bromide
CAS No.	21450-64-6
Molecular Formula	C8H9BrMg
Molecular Weight	209.36 g/mol
Synonyms	2,6-Dimethylphenylmagnesium Bromide; 2,6-Xylylmagnesium Bromide; (2,6-Dimethylphenyl)magnesium Bromide; Magnesium, bromo(2,6-dimethylphenyl)-; Bromo(2,6-dimethylphenyl)magnesium; Grignard Reagent (2,6-Dimethylphenyl); 2,6-Dimethylbenzylmagnesium Bromide (common misnomer)
EINECS	Contact for details

Quality Control

Our 2,6-Dimethylphenylmagnesium Bromide is manufactured under stringent quality control protocols to ensure batch-to-batch consistency and high reactivity. Each lot is analyzed to confirm concentration (typically supplied as a solution in THF or diethyl ether) and the absence of significant protic impurities. A comprehensive Certificate of Analysis (COA) detailing assay, titration results, and solvent content is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. This product is highly volatile, easily oxidized, and reacts violently with protic substances. It must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry, and well-ventilated area, away from heat, sparks, and open flames. Due to its pyrophoric nature and sensitivity to moisture and oxygen, handling should only be performed using standard Schlenk line or glovebox techniques.

Specification

Item	Specification
Appearance	Clear, colorless to light brown solution
Concentration	0.5 M to 2.0 M in specified solvent (typically THF or Et2O)
Assay (Titration)	≥ 95% of stated concentration
Solvent	Specified anhydrous ether or tetrahydrofuran
Water Content (Karl Fischer)	≤ 50 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.