Description

Picrotin CAS NO 21416-53-5 is a specific, naturally occurring diterpenoid compound, a key component of the potent neurotoxin picrotoxin. This high-purity reference standard is critical for research and development in neuroscience and pharmacology. It is primarily utilized by pharmaceutical researchers, toxicologists, and analytical laboratories for method development, calibration, and investigative studies.

Application

• Neuroscience Research: Used as a reference standard in studies investigating GABAA receptor antagonism and central nervous system (CNS) activity.
• Pharmacological Studies: Employed in the development and validation of assays for convulsant and antidote research.
• Analytical Chemistry: Serves as a high-purity calibration standard for HPLC, LC-MS, and other chromatographic methods in forensic and pharmaceutical analysis.
• Toxicology: Used as a precise analytical marker in the identification and quantification of picrotoxin components in various matrices.
• Biochemical Reagent: Applied in vitro studies to probe ion channel function and synaptic transmission mechanisms.
• Pharmaceutical Impurity Profiling: Acts as a known impurity or related substance standard in the quality control of certain pharmaceutical compounds.

Basic Information

Product Name	Picrotin
CAS No.	21416-53-5
Molecular Formula	C15H18O7
Molecular Weight	310.30 g/mol
Synonyms	Picrotin; (1R,2S,5S,7S,8R,9S,10R)-5,8,9-Trihydroxy-4,4,7,10-tetramethyl-3,14-dioxatetracyclo[5.5.1.02,5.08,10]tetradecane-13-one; NSC 15398; Picrotoxin component; Anamirtin
EINECS	244-387-1

Quality Control

Our Picrotin is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets the stringent requirements for research-grade materials. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, purity, and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.