Description

Piperazine, 1-(2-Amino-1,1-Dimethylethyl)-4-Methyl- (8Ci) CAS NO 21404-92-2 is a specialized piperazine derivative featuring a tert-butylamino side chain, which imparts unique steric and chemical properties. This compound serves as a critical high-value intermediate in the synthesis of complex molecules, particularly in pharmaceutical development. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its modified piperazine scaffold.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands or metal-organic frameworks (MOFs) used in asymmetric catalysis.
• Polymer Modification: Acts as a functional monomer or cross-linking agent for specialty polymers with enhanced thermal or mechanical properties.
• Chemical Research & Development: Essential for academic and industrial research exploring new chemical entities and reaction pathways.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-purity specialty chemicals.

Basic Information

Product Name	Piperazine, 1-(2-Amino-1,1-Dimethylethyl)-4-Methyl- (8Ci)
CAS No.	21404-92-2
Molecular Formula	C9H21N3
Molecular Weight	171.29 g/mol
Synonyms	1-(2-Amino-2-methylpropyl)-4-methylpiperazine; 4-Methyl-1-(2-amino-1,1-dimethylethyl)piperazine; 1-(1-Amino-2-methyl-2-propyl)-4-methylpiperazine; N-(2-Amino-1,1-dimethylethyl)-N'-methylpiperazine; tert-Butylaminomethyl methylpiperazine; 2-[(4-Methylpiperazin-1-yl)methyl]propan-2-amine
EINECS	Contact for details

Quality Control

Our Piperazine, 1-(2-Amino-1,1-Dimethylethyl)-4-Methyl- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC, GC, and NMR to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles where applicable, ensuring the material meets the stringent requirements for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.