Description

2-(Triphenyl-Phosphanylidene)-Propionic Acid Ethyl Ester is a specialized Wittig reagent and a key organophosphorus synthon. This compound matters for its critical role in facilitating carbon-carbon double bond formation, particularly in the synthesis of α,β-unsaturated esters. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate Synthesis: A crucial reagent for the Wittig olefination reaction in the production of active pharmaceutical ingredients (APIs), especially those containing α,β-unsaturated ester functionalities.
• Agrochemical Manufacturing: Used in the synthesis of complex organic molecules for crop protection agents and pesticides.
• Fine Chemical Production: Employed in the preparation of specialty chemicals, flavors, and fragrances requiring specific alkene geometries.
• Material Science Research: Serves as a building block in the development of novel polymers and organic electronic materials.
• Academic & Industrial R&D: A valuable tool in organic synthesis laboratories for method development and the construction of complex natural products.
• Process Chemistry: Utilized in scaling up synthetic routes from laboratory to pilot plant and commercial production.

Basic Information

Product Name	2-(Triphenyl-Phosphanylidene)-Propionic Acid Ethyl Ester
CAS No.	21382-82-1
Molecular Formula	C23H21O2P
Molecular Weight	360.39 g/mol
Synonyms	(Ethoxycarbonylethylidene)triphenylphosphorane; Ethyl 2-(triphenylphosphoranylidene)propionate; Ethyl (triphenylphosphoranylidene)propionate; Ethyl 3-(triphenylphosphoranylidene)butanoate; 2-(Triphenylphosphoranylidene)propionic acid ethyl ester; Carboethoxymethylenetriphenylphosphorane homolog; Wittig reagent for α,β-unsaturated ester synthesis
EINECS	Contact for details

Quality Control

Our 2-(Triphenyl-Phosphanylidene)-Propionic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and titration methods, to ensure high purity and consistent performance as a Wittig reagent. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.