Description

5-Chloropyrazine-2-Carboxamide is a versatile heterocyclic building block and key synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce functionalized pyrazine motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various drug candidates, including kinase inhibitors and other biologically active heterocycles.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that incorporate the pyrazine scaffold.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in coordination chemistry and catalysis.
• Material Science Research: Employed in the development of organic electronic materials and metal-organic frameworks (MOFs) due to its functional groups.
• Custom Synthesis and Contract Manufacturing: A key building block for custom synthesis projects and scale-up services for clients in life sciences.

Basic Information

Product Name	5-Chloropyrazine-2-Carboxamide
CAS No.	21279-64-1
Molecular Formula	C5H4ClN3O
Molecular Weight	157.56 g/mol
Synonyms	2-Amino-5-chloropyrazine; 5-Chloro-2-pyrazinecarboxamide; 5-Chloropyrazinecarboxamide; 2-Pyrazinecarboxamide, 5-chloro-; 5-Chloro-2-carbamoylpyrazine; 5-Chloropyrazine-2-carboxylic acid amide; 5-Chloro-2-pyrazinecarboxylic acid amide; 5-Chloro-2-pyrazinecarboxylic acid, amide
EINECS	Contact for details

Quality Control

Our 5-Chloropyrazine-2-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.