Description

3-Chloropyrazine-2-Carboxamide is a versatile and high-value heterocyclic building block primarily used in advanced organic synthesis. This compound is critical for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs) and agrochemicals due to its reactive chloropyrazine core. It is particularly sought after by the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology therapeutics.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the pyrazine moiety for biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating novel ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as conductive polymers and molecular semiconductors.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Academic and R&D Laboratories: Essential for medicinal chemistry programs and exploratory research in heterocyclic chemistry.

Basic Information

Product Name	3-Chloropyrazine-2-Carboxamide
CAS No.	21279-62-9
Molecular Formula	C5H4ClN3O
Molecular Weight	157.56 g/mol
Synonyms	2-Chloropyrazine-3-carboxamide; 3-Chloro-2-pyrazinecarboxamide; 3-Chloro-pyrazine-2-carboxylic acid amide; 2-Pyrazinecarboxamide, 3-chloro-; 3-Chloropyrazinecarboxamide; 3-Chloro-2-carbamoylpyrazine; 3-Chloropyrazine-2-carboxylic acid amide
EINECS	Contact for details

Quality Control

Our 3-Chloropyrazine-2-Carboxamide is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent performance. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP (current Good Manufacturing Practice) standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.