Description

(2-Fluoro-Phenyl)-(4-Methyl-Piperazin-1-Yl)-Methanone is a high-purity, specialized organic building block featuring a fluorinated aromatic ketone core linked to a methylpiperazine moiety. This compound is critical for pharmaceutical research and development, serving as a versatile intermediate in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors seeking to incorporate its unique fluorinated pharmacophore into new molecular entities.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, particularly in central nervous system (CNS) and oncology research programs.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the fluorine atom can enhance biological activity and metabolic stability.
• Chemical Biology Probe Synthesis: Employed in creating molecular tools and probes for studying biological pathways and protein interactions.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced organic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or research-grade conditions.

Basic Information

Product Name	(2-Fluoro-Phenyl)-(4-Methyl-Piperazin-1-Yl)-Methanone
CAS No.	20929-25-3
Molecular Formula	C12H15FN2O
Molecular Weight	222.26 g/mol
Synonyms	1-(2-Fluorobenzoyl)-4-methylpiperazine; 4-Methyl-1-(2-fluorobenzoyl)piperazine; (2-Fluorophenyl)(4-methyl-1-piperazinyl)methanone; 2-Fluoro-N-(4-methylpiperazin-1-yl)benzamide; N-(4-Methylpiperazin-1-yl)-2-fluorobenzamide; 20929-25-3; 2-Fluorophenyl 4-methylpiperazin-1-yl ketone
EINECS	Contact for details

Quality Control

Our (2-Fluoro-Phenyl)-(4-Methyl-Piperazin-1-Yl)-Methanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.