Description

(S)-2-Bromosuccinic Acid CAS NO 20859-23-8 is a high-purity chiral building block essential for asymmetric synthesis in advanced pharmaceutical and agrochemical research. Its value lies in providing a stereochemically defined succinate framework for constructing complex molecules with high enantiomeric purity. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, fine chemical, and specialty materials industries for developing new active ingredients and functional intermediates.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in protease inhibitors and other therapeutic agents.
• Asymmetric Catalyst Ligand Precursor: Used to develop novel chiral ligands for transition metal catalysis in enantioselective reactions.
• Agrochemical Research: Building block for creating chiral herbicides, fungicides, and plant growth regulators with improved efficacy and selectivity.
• Peptidomimetics & Bioactive Molecule Synthesis: Incorporates a functionalized, stereocontrolled succinic acid moiety into peptide analogs and other bioactive compounds.
• Polymer Modification: Serves as a monomer or cross-linking agent for introducing bromine functionality and chirality into specialty polymers.
• Academic & Discovery Chemistry: A valuable reagent in academic laboratories for methodological development in organic synthesis and stereochemistry studies.

Basic Information

Product Name	(S)-2-Bromosuccinic Acid
CAS No.	20859-23-8
Molecular Formula	C4H5BrO4
Molecular Weight	197.00 g/mol
Synonyms	(S)-2-Bromobutanedioic Acid; (S)-Bromosuccinic Acid; L-2-Bromosuccinic Acid; (2S)-2-Bromobutanedioic Acid; (S)-(-)-2-Bromosuccinic Acid; Succinic Acid, 2-Bromo-, (S)-; Butanedioic acid, 2-bromo-, (2S)-
EINECS	Contact for details

Quality Control

Our (S)-2-Bromosuccinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing identity, purity (typically ≥98%), enantiomeric excess (ee), and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator or inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.