Description

2-Hydroxy-6-Methylpyrazine is a versatile heterocyclic compound that serves as a crucial building block and intermediate in advanced organic synthesis. Its unique pyrazine core with hydroxyl and methyl substituents makes it valuable for modifying chemical and physical properties in target molecules. This high-purity intermediate is essential for research and production in the pharmaceutical and agrochemical sectors, where precise molecular architecture is required.

Application

2-Hydroxy-6-Methylpyrazine CAS NO 20721-18-0 is a key synthetic intermediate with applications across several high-value industries.

• Pharmaceutical Intermediates: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly those with pyrazine-based structures for various therapeutic areas.
• Agrochemical Synthesis: Serves as a precursor in the development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic framework.
• Ligand and Chelator Preparation: Utilized in coordination chemistry to create specialized ligands for catalysis or metal ion sequestration.
• Flavor and Fragrance Industry: Acts as a starting material for synthesizing complex aroma compounds, contributing roasted, nutty notes.
• Material Science Research: Employed in the development of organic electronic materials, dyes, and photoactive compounds.
• Chemical Research & Development: A valuable building block for medicinal chemistry and process development in contract research organizations (CROs) and CDMOs.

Basic Information

Product Name	2-Hydroxy-6-Methylpyrazine
CAS No.	20721-18-0
Molecular Formula	C5H6N2O
Molecular Weight	110.11 g/mol
Synonyms	6-Methyl-2(1H)-pyrazinone; 6-Methyl-2-pyrazinol; 2-Hydroxy-6-methylpyrazine; 6-Methyl-2-hydroxypyrazine; 2-Pyrazinol, 6-methyl-; 2(1H)-Pyrazinone, 6-methyl-; 6-Methyl-1H-pyrazin-2-one; 6-Methylpyrazin-2-ol
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-6-Methylpyrazine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.