Description

(Diethoxymethyl)Diphenylphosphine Oxide is a specialized organophosphorus compound that serves as a versatile intermediate in advanced chemical synthesis. Its unique structure, featuring both phosphine oxide and acetal functionalities, makes it a valuable reagent for constructing complex molecular architectures. This chemical is primarily sought after by research institutions and industrial R&D departments engaged in the development of pharmaceuticals, agrochemicals, and novel materials. Its utility lies in facilitating key transformations, such as Horner-Wadsworth-Emmons (HWE) olefination reactions, to create carbon-carbon double bonds with precise stereochemical control.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for olefin-containing drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where specific alkene geometries are required for biological activity.
• Material Science Research: Employed in the development of specialty polymers, ligands for catalysis, and organic electronic materials.
• Academic & Industrial R&D: A crucial reagent in organic synthesis laboratories for method development and the construction of complex, unsaturated molecules.
• Fine Chemical Production: Serves as a precursor in the multi-step synthesis of flavors, fragrances, and other high-value specialty chemicals.

Basic Information

Product Name	(Diethoxymethyl)Diphenylphosphine Oxide
CAS No.	20570-20-1
Molecular Formula	C₁₇H₂₁O₃P
Molecular Weight	304.32 g/mol
Synonyms	Diethoxymethyl(diphenyl)phosphine oxide; (Diethoxymethyl)diphenylphosphine oxide; Diphenyl(diethoxymethyl)phosphine oxide; Phosphine oxide, (diethoxymethyl)diphenyl-; (Diethoxymethyl)diphenyl-oxophosphorane; Acetaldehyde diethyl acetal, diphenylphosphinyl-
EINECS	Contact for details

Quality Control

Every batch of (Diethoxymethyl)Diphenylphosphine Oxide is produced and tested under a strict quality management system to ensure consistency and reliability for your critical applications. Our products undergo rigorous quality testing, including chromatographic purity analysis and identity confirmation, to meet the high standards required for research and industrial synthesis. Certificates of Analysis (COA) documenting key parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.