Description

(3Ar)-3A,4,5,6,6Aβ,7,9Aβ,9Bα-Octahydro-4β-Acetoxy-6,9-Dimethyl-6β-Hydroxy-3-Methyleneazuleno[4,5-B]Furan-2(3H)-One is a complex sesquiterpene lactone derivative, a class of compounds known for their significant biological activity. This high-purity intermediate is critical for research and development in advanced pharmaceutical synthesis, particularly for its potential as a precursor in anti-inflammatory and anticancer agent discovery. It is primarily sought after by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and natural product synthesis.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block for the synthesis of novel therapeutic agents, especially in oncology and immunology research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new sesquiterpene lactone-based drugs with improved efficacy and reduced toxicity.
• Natural Product Synthesis: Acts as a synthetic target or intermediate in the total synthesis of complex natural products for biological evaluation.
• Biochemical Research: Employed as a reference standard or probe in studies investigating biological pathways and enzyme inhibition.
• Fine Chemical Production: Utilized in the multi-step synthesis of high-value, specialized chemicals for advanced material science applications.

Basic Information

Product Name	(3Ar)-3A,4,5,6,6Aβ,7,9Aβ,9Bα-Octahydro-4β-Acetoxy-6,9-Dimethyl-6β-Hydroxy-3-Methyleneazuleno[4,5-B]Furan-2(3H)-One
CAS No.	20482-33-1
Molecular Formula	C17H22O5
Molecular Weight	306.36 g/mol
Synonyms	4β-Acetoxy-6β-hydroxy-6,9-dimethyl-3-methylenecis,cis,trans-2,3,3a,4,5,6,6aβ,7,9aβ,9bα-decahydroazuleno[4,5-b]furan-2-one; 4β-Acetoxy-6β-hydroxy-6,9-dimethyl-3-methylenedecahydroazuleno[4,5-b]furan-2-one; Alantolactone derivative; Isoalantolactone acetate derivative; Sesquiterpene lactone acetate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized and tested to meet stringent specifications for identity, purity, and impurity profiles, supporting cGMP and ICH Q7 guidelines for advanced pharmaceutical intermediates. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.