Description

2-Methylbutyl Carbonochloridate is a specialized organic reagent primarily used as a versatile acylating and chloroformylating agent in chemical synthesis. Its value lies in its ability to efficiently introduce the 2-methylbutyloxycarbonyl protecting group or serve as a key building block for more complex molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity intermediates for advanced synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing specific ester or carbamate functionalities.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the 2-methylbutyl moiety is required for biological activity.
• Peptide Chemistry: Acts as a reagent for the temporary protection of amino groups during solid-phase and solution-phase peptide synthesis.
• Polymer Chemistry: Employed as a monomer or modifying agent in the production of specialty polycarbonates and polyurethanes with tailored properties.
• Organic Synthesis Reagent: A versatile acyl chloride used in esterification, amidation, and other nucleophilic substitution reactions under mild conditions.
• Chemical Research & Development: Serves as a critical tool for medicinal chemists and process researchers exploring new synthetic pathways and novel compound libraries.

Basic Information

Product Name	2-Methylbutyl Carbonochloridate
CAS No.	20412-39-9
Molecular Formula	C6H11ClO2
Molecular Weight	150.60 g/mol
Synonyms	2-Methylbutyl Chloroformate; Isoamyl Chloroformate; 3-Methylbutyl Chloroformate; Isopentyl Chloroformate; Carbonochloridic Acid, 2-Methylbutyl Ester; Chloroformic Acid Isoamyl Ester; Isoamyloxycarbonyl Chloride
EINECS	243-815-0

Quality Control

Our 2-Methylbutyl Carbonochloridate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and titration methods, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at temperatures between 2°C and 8°C (refrigerated) for extended stability. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Acidity (as HCl)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.