Description

1-Palmitoyl-2-Stearoyl-Rac-Glycerol is a synthetic, racemic triacylglycerol (TAG) composed of palmitic and stearic acid residues. This structured lipid is valued for its defined composition and purity, making it a critical reference standard and a versatile building block for advanced lipid research and formulation. It is essential for researchers and manufacturers in the pharmaceutical, nutraceutical, and specialty chemical industries who require high-purity, well-characterized lipids for analytical calibration, metabolic studies, and the development of lipid-based delivery systems.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quantification and identification of complex lipids in drug formulations and biological samples via techniques like HPLC and mass spectrometry.
• Lipidomics Research: Serves as a critical calibrant and internal standard in mass spectrometry-based lipidomic studies to understand lipid metabolism and cell signaling pathways.
• Biochemical Substrate: Employed as a defined substrate for studying the activity, specificity, and kinetics of lipases, phospholipases, and other lipid-metabolizing enzymes.
• Lipid-Based Drug Delivery Systems: Acts as a model excipient or core lipid in the research and development of solid lipid nanoparticles (SLNs), nanoemulsions, and other advanced drug carriers.
• Nutritional Science: Utilized in metabolic studies to investigate the absorption, transport, and utilization of specific saturated fatty acids in structured triglyceride form.
• Cosmetic Ingredient Research: Applied in the formulation and testing of high-end cosmetic products for its emollient properties and stable lipid matrix.

Basic Information

Product Name	1-Palmitoyl-2-Stearoyl-Rac-Glycerol
CAS No.	20296-26-8
Molecular Formula	C55H106O6
Molecular Weight	863.43 g/mol
Synonyms	rac-1-Palmitoyl-2-stearoyl-glycerol; Glyceryl 1-palmitate 2-stearate; PSP; TAG(16:0/18:0/0:0); 1-Hexadecanoyl-2-octadecanoyl-rac-glycerol; Glycerol 1-palmitoyl-2-stearoyl ether; Palmitic-stearic acid triglyceride; rac-PSP
EINECS	243-686-1

Quality Control

Every batch of 1-Palmitoyl-2-Stearoyl-Rac-Glycerol is manufactured and analyzed under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency, which is critical for its use as a reference material. A detailed Certificate of Analysis (COA) specifying purity by HPLC, identity confirmation by FT-IR or NMR, and impurity profiles is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) to minimize oxidation. For long-term storage, keep desiccated. Allow the sealed container to reach room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.