Description

1,2-Dimyristoylphosphatidylethanolamine (DMPE) is a high-purity, synthetic phospholipid essential for constructing stable, functional lipid bilayers in advanced research and formulation. This compound is critical for applications requiring precise membrane modeling and controlled surface properties. It is primarily utilized by researchers and product developers in the pharmaceutical, biotechnology, and advanced material science sectors for liposome preparation, drug delivery systems, and membrane protein studies.

Application

• Liposome & Nanoparticle Formulation: A key structural component for creating unilamellar and multilamellar vesicles for drug encapsulation.
• Drug Delivery Systems: Used in the development of targeted and sustained-release therapeutic carriers, including mRNA-LNPs (lipid nanoparticles).
• Membrane Biochemistry Research: Serves as a model membrane lipid for studying protein-lipid interactions, membrane fusion, and permeability.
• Biomimetic Coatings & Sensors: Employed to create functionalized surfaces and biosensors that mimic natural cell membranes.
• Cell Culture & Transfection Reagents: A component in specialized media and reagents to enhance cell membrane stability and transfection efficiency.
• Cosmetic & Dermatological Formulations: Used in high-end skincare products as a skin-identical lipid to improve barrier function and delivery of active ingredients.

Basic Information

Product Name	1,2-Dimyristoylphosphatidylethanolamine
CAS No.	20255-95-2
Molecular Formula	C33H66NO8P
Molecular Weight	635.85 g/mol
Synonyms	DMPE; 1,2-Ditetradecanoyl-sn-glycero-3-phosphoethanolamine; Dimyristoylphosphatidylethanolamine; Phosphatidylethanolamine, 1,2-dimyristoyl; PE(14:0/14:0); DMPE-Na (Sodium Salt); 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine; DMPC (Note: DMPC is a common but distinct phosphatidylcholine; listed here for clarity and search relevance).
EINECS	243-626-1

Quality Control

Our 1,2-Dimyristoylphosphatidylethanolamine is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and GMP-grade applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, residual solvents, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Phase Transition Temperature (Tm)	~ 50°C
Loss on Drying	≤ 2.0 %
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.