Description

2-Nitrophenoxyacetyl Chloride is a specialized organic acid chloride derivative used as a key building block in advanced chemical synthesis. This compound matters for its role as a reactive intermediate, enabling the efficient introduction of the 2-nitrophenoxyacetyl moiety into target molecules. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and production of herbicides, pesticides, and plant growth regulators.
• Peptide Chemistry: Acts as an acylating agent for the protection or modification of amino acids and peptides.
• Dye and Pigment Manufacturing: Employed in the synthesis of complex organic dyes and colorants.
• Polymer Science: Functions as a monomer or cross-linking agent in the production of specialty polymers and resins.
• Chemical Research: Utilized in academic and industrial R&D for exploring new organic reactions and methodologies.
• Ligand and Catalyst Preparation: Used to synthesize specialized ligands for metal complexes and catalysts.

Basic Information

Product Name	2-Nitrophenoxyacetyl Chloride
CAS No.	20142-87-4
Molecular Formula	C8H6ClNO4
Molecular Weight	215.59 g/mol
Synonyms	2-Nitrophenoxyacetyl chloride; (2-Nitrophenoxy)acetyl chloride; Acetyl chloride, 2-(2-nitrophenoxy)-; o-Nitrophenoxyacetyl chloride; 2-(2-Nitrophenoxy)acetyl chloride; NSC 163081; 2-Nitro-phenoxy-acetyl chloride
EINECS	Contact for details

Quality Control

Our 2-Nitrophenoxyacetyl Chloride undergoes rigorous quality testing to ensure compliance with industry standards. We implement strict in-process controls and final batch analysis to guarantee high purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. Our quality management system supports traceability and meets the demands of cGMP and ISO standards for critical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation from moisture. Keep away from heat, open flames, and incompatible materials such as bases, alcohols, and oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.