Description

Calcium Dobesilate is an organosulfur compound with significant therapeutic and industrial applications. This high-purity active pharmaceutical ingredient (API) is valued for its role in vascular protection and microcirculation improvement. It is primarily utilized by pharmaceutical manufacturers and research institutions developing treatments for chronic venous insufficiency and diabetic retinopathy. Our supply ensures consistent quality and reliable availability for global B2B partners.

Application

• Pharmaceutical API: Primary use as the active ingredient in medications for chronic venous disorders and diabetic microangiopathy.
• Vascular Protectant Formulations: Key component in capsules, tablets, and injectables designed to reduce capillary permeability and fragility.
• Ophthalmic Preparations: Used in the research and production of treatments for diabetic retinopathy and other retinal vascular diseases.
• Clinical Research: Serves as a reference standard and raw material in pharmacological studies and new drug development.
• Veterinary Pharmaceuticals: Incorporated into treatments for vascular conditions in animals.
• Intermediate Synthesis: Acts as a chemical intermediate in the synthesis of more complex organosulfur compounds.

Basic Information

Product Name	Calcium Dobesilate
CAS No.	20123-80-2
Molecular Formula	C12H10CaO10S2
Molecular Weight	418.40 g/mol
Synonyms	Calcium Dobesilate; Calcium Doxium; Doxium; Calcium 2,5-dihydroxybenzenesulfonate; Dobesilate Calcium; 2,5-Dihydroxybenzenesulfonic Acid Calcium Salt; Calcium 2,5-Dihydroxybenzenesulfonate
EINECS	243-531-5

Quality Control

Our Calcium Dobesilate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical use. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%
Microbial Limits	Conforms to EP/JP/USP requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.