Description

2-[2-[4-(p-Chloro-α-2-Pyridylbenzyl)Piperazin-1-Yl]Ethoxy]Ethanol Hydrochloride is a high-purity, pharmaceutically relevant piperazine derivative. This compound serves as a critical intermediate in the synthesis of advanced active pharmaceutical ingredients (APIs), offering significant value in research and development. It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules, particularly in central nervous system (CNS) and cardiovascular research.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the production route for specific, high-value APIs requiring its unique piperazine-based structure.
• Medicinal Chemistry Research: A valuable scaffold for structure-activity relationship (SAR) studies and the discovery of new chemical entities in pharmaceutical R&D labs.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials and commercial APIs.
• Biochemical Research: Potential use as a tool compound in biochemical assays and pharmacological studies due to its receptor-interacting properties.

Basic Information

Product Name	2-[2-[4-(p-Chloro-α-2-Pyridylbenzyl)Piperazin-1-Yl]Ethoxy]Ethanol Hydrochloride
CAS No.	2850-44-4
Molecular Formula	C20H27Cl2N3O2
Molecular Weight	412.35 g/mol
Synonyms	2-[2-[4-[(4-Chloro-2-pyridinyl)phenylmethyl]-1-piperazinyl]ethoxy]ethanol hydrochloride; 1-[(4-Chloro-2-pyridinyl)phenylmethyl]-4-[2-(2-hydroxyethoxy)ethyl]piperazine hydrochloride; 2-{2-[4-[(4-Chloro-2-pyridinyl)benzyl]piperazin-1-yl]ethoxy}ethanol hydrochloride; 2850-44-4; UNII-9Q8T0F2Q6S; 9Q8T0F2Q6S; CHEMBL3183455; CTK0H7561; AKOS015915176
EINECS	Contact for details

Quality Control

Our 2-[2-[4-(p-Chloro-α-2-Pyridylbenzyl)Piperazin-1-Yl]Ethoxy]Ethanol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications suitable for pharmaceutical development. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request, supporting regulatory submissions and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.