Description

3-Amino-6-Chloropyrazine-2-Carboxylic Acid is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is valued for its unique pyrazine core, which serves as a versatile scaffold for constructing complex molecules with targeted biological activity. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for antiviral, anticancer, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging its heterocyclic structure.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the manufacture of dyes, pigments, and other specialty chemicals requiring a functionalized pyrazine moiety.
• Academic and R&D: A valuable reagent for medicinal chemistry research, process development, and exploring new synthetic methodologies in university and corporate laboratories.

Basic Information

Product Name	3-Amino-6-Chloropyrazine-2-Carboxylic Acid
CAS No.	2727-13-1
Molecular Formula	C5H4ClN3O2
Molecular Weight	173.56 g/mol
Synonyms	6-Chloro-3-aminopyrazine-2-carboxylic acid; 3-Amino-6-chloro-2-pyrazinecarboxylic acid; 2-Pyrazinecarboxylic acid, 3-amino-6-chloro-; 6-Chloro-3-aminopyrazinecarboxylic acid; 3-Amino-6-chloropyrazinecarboxylic acid; 3-Amino-6-chloro-2-carboxypyrazine; 2727-13-1; AC1L1B4H
EINECS	220-333-6

Quality Control

Our 3-Amino-6-Chloropyrazine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay, impurity profile, and residual solvents. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP-compliant production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.