Description

15-Acetoxy-3Alpha,4Beta-Dihydroxy-12,13-Epoxytrichothec-9-Ene is a complex trichothecene derivative, a class of sesquiterpenoid compounds known for their potent biological activity. This compound serves as a critical advanced intermediate and reference standard in pharmaceutical research and development. It is primarily utilized by research institutions and specialty chemical manufacturers focused on oncology, mycology, and novel therapeutic agent synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex bioactive molecules and potential drug candidates.
• Biochemical Research: Reference standard and tool compound for studying trichothecene biosynthesis, toxicity, and mode of action.
• Antifungal Agent Development: Serves as a precursor or model compound in the development of novel antifungal agents.
• Toxicology Studies: Used as a calibrated standard in analytical methods (e.g., HPLC, LC-MS) for detecting and quantifying trichothecene mycotoxins.
• Academic Research: Employed in chemical biology and medicinal chemistry programs to explore structure-activity relationships (SAR).
• Standards Manufacturing: Production of certified reference materials (CRMs) for food safety and agricultural testing laboratories.

Basic Information

Product Name	15-Acetoxy-3Alpha,4Beta-Dihydroxy-12,13-Epoxytrichothec-9-Ene
CAS No.	2623-22-5
Molecular Formula	C17H22O7
Molecular Weight	338.35 g/mol
Synonyms	3α,4β-Dihydroxy-15-acetoxy-12,13-epoxytrichothec-9-ene; 15-Acetoxy-3α,4β-dihydroxy-12,13-epoxytrichothec-9-ene; 12,13-Epoxytrichothec-9-ene-3α,4β,15-triol 15-acetate; Trichodermol 15-acetate; (3α,4β)-3,4,15-Trihydroxy-12,13-epoxytrichothec-9-en-15-yl acetate; 4β,15-Diacetoxy-3α-hydroxy-12,13-epoxytrichothec-9-ene (common misnomer); NSC 178248; Trichothec-9-ene-3α,4β,15-triol, 15-acetate, 12,13-epoxy-
EINECS	Contact for details

Quality Control

Our 15-Acetoxy-3Alpha,4Beta-Dihydroxy-12,13-Epoxytrichothec-9-Ene is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic methods (NMR, IR, MS) for structural confirmation, to ensure identity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support cGMP and ISO compliant manufacturing for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.