Description

Coronopilin is a naturally occurring sesquiterpene lactone compound, identified by CAS NO 2571-81-5. This bioactive molecule is valued for its significant potential in pharmaceutical research and development, particularly due to its studied biological activities. It is a critical intermediate and reference standard for researchers and manufacturers in the life sciences sector. Industries focused on drug discovery, phytochemical analysis, and natural product synthesis are the primary users of this high-purity compound.

Application

• Pharmaceutical Research: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the development of novel therapeutic agents.
• Biological Studies: Used as a pure compound to investigate anti-inflammatory, cytotoxic, and other pharmacological properties in vitro and in vivo.
• Natural Product Isolation: Acts as a marker compound for the quality control and standardization of botanical extracts, particularly from the Ambrosia genus.
• Chemical Synthesis: Provides a structurally complex scaffold for the semi-synthesis of derivatives with enhanced or modified bioactivity.
• Academic Research: Employed in universities and research institutes for studies in medicinal chemistry, pharmacology, and plant biochemistry.

Basic Information

Product Name	Coronopilin
CAS No.	2571-81-5
Molecular Formula	C15H18O4
Molecular Weight	262.30 g/mol
Synonyms	Coronopilin; (-)-Coronopilin; 4,5-Epoxy-6-hydroxygermacra-1(10),11(13)-dien-12-oic acid 12,6-lactone; Ambrosin; 1(10),4,11(13)-Germacratrien-12-oic acid, 4,5-epoxy-6-hydroxy-, γ-lactone; Parthenin isomer
EINECS	Contact for details

Quality Control

Our Coronopilin is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and related substance profiling, to meet the stringent requirements of research and development. A Certificate of Analysis (COA) detailing identity, purity, and other critical parameters is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.