Description

Bufexamac is a non-steroidal anti-inflammatory drug (NSAID) belonging to the class of para-aminophenol derivatives, primarily recognized for its topical anti-inflammatory and analgesic properties. Its value lies in its specific mechanism of action, which effectively targets localized inflammation and pain, making it a key active pharmaceutical ingredient (API) for targeted therapeutic formulations. This compound is essential for manufacturers in the pharmaceutical and personal care industries developing topical creams, ointments, and gels for conditions like dermatitis, eczema, and muscle pain.

Application

• Topical Anti-inflammatory Preparations: Primary use as the active ingredient in creams, ointments, and gels for treating skin inflammation, contact dermatitis, and eczema.
• Analgesic Formulations: Incorporated into topical products designed for the relief of muscle aches, joint pain, and minor arthritis.
• Veterinary Pharmaceuticals: Used in topical treatments for inflammatory skin conditions in animals.
• Cosmaceutical Products: Potential ingredient in formulations aimed at reducing skin redness and irritation.
• Pharmaceutical Intermediates: Serves as a chemical building block in the synthesis of more complex drug molecules.
• Research & Development: Utilized in biochemical and pharmacological research to study inflammation pathways and NSAID mechanisms.

Basic Information

Product Name	Bufexamac
CAS No.	2438-72-4
Molecular Formula	C12H17NO3
Molecular Weight	223.27 g/mol
Synonyms	2-(4-Butoxyphenyl)-N-hydroxyacetamide; Butexamac; Bufexamic acid; Droxaryl; Flogocid; Paraderm; Parfenac; 4-Butoxy-N-hydroxybenzeneacetamide; p-Butoxy-N-hydroxybenzeneacetamide; BRN 2209482; NSC 77625
EINECS	219-432-2

Quality Control

Our Bufexamac is produced under strict quality management systems to ensure it meets the high standards required for pharmaceutical applications. Each batch undergoes comprehensive analytical testing, including identification, assay, and impurity profiling via techniques like HPLC and IR spectroscopy. We adhere to relevant ICH guidelines and can supply material compliant with customer-specific pharmacopeial requirements. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee purity, identity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.