Description

2-Bromobutanoic Acid is a versatile chiral building block and alkylating agent essential for advanced organic synthesis. Its reactive bromine and carboxylic acid functionalities make it a critical intermediate for constructing complex molecules with high stereochemical control. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Key starting material for the synthesis of active pharmaceutical ingredients (APIs), particularly in the production of non-steroidal anti-inflammatory drugs (NSAIDs) and other chiral therapeutics.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and plant growth regulators where the butanoic acid moiety is required.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptide Modification: Employed to introduce bromoalkyl side chains into peptides and amino acid derivatives for structure-activity relationship (SAR) studies.
• Polymer Science: Acts as a monomer or chain-transfer agent in the synthesis of specialized polymers and functional materials.
• Organic Synthesis Reagent: Utilized in various name reactions, including nucleophilic substitution and carbon-carbon bond-forming reactions, to install the 2-bromobutanoate group.

Basic Information

Product Name	2-Bromobutanoic Acid
CAS No.	2385-70-8
Molecular Formula	C4H7BrO2
Molecular Weight	167.00 g/mol
Synonyms	2-Bromobutyric Acid; (±)-2-Bromobutanoic Acid; α-Bromobutyric Acid; DL-2-Bromobutanoic Acid; Butanoic acid, 2-bromo-; 2-Bromobuttersäure (German); Acide 2-bromobutanoïque (French); NSC 406079
EINECS	219-207-7

Quality Control

Our 2-Bromobutanoic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing specific results for assay, impurities, and physical properties is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. Due to its nature as a strong acid/organic solvent, handle with appropriate personal protective equipment in a fume hood.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.470 - 1.476
Specific Gravity (20°C)	1.56 - 1.62

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.