Description

3-Butynoic Acid is a versatile alkyne-containing carboxylic acid, serving as a critical building block in advanced organic synthesis. Its terminal alkyne and carboxylic acid functionalities make it a valuable precursor for constructing complex molecular architectures through click chemistry and cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the production of active pharmaceutical ingredients (APIs), particularly those requiring alkyne motifs for further derivatization.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for creating specialty polymers with tailored properties.
• Bioconjugation & Probe Development: Ideal for labeling biomolecules (proteins, peptides, nucleic acids) via copper-catalyzed azide-alkyne cycloaddition (CuAAC) click chemistry.
• Ligand & Catalyst Preparation: Employed in the synthesis of specialized ligands for metal-organic frameworks (MOFs) and homogeneous catalysis.
• Organic Synthesis Building Block: Used in Sonogashira coupling, amidation, esterification, and other reactions to introduce the butynoic acid moiety.

Basic Information

Product Name	3-Butynoic Acid
CAS No.	2345-51-9
Molecular Formula	C4H4O2
Molecular Weight	84.07 g/mol
Synonyms	But-3-ynoic Acid; 3-Butyn-1-oic Acid; Propiolylcarbinol; Tetrolic Acid (Note: Tetrolic acid is 2-Butynoic acid, a common mis-association); 3-Butynic Acid; Acetyleneacetic Acid; 3-Butynoate; 2345-51-9 (CAS RN)
EINECS	Contact for details

Quality Control

Our 3-Butynoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and industrial applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Due to its nature as a strong acid/organic solvent, containers must be kept tightly sealed to prevent moisture absorption and potential decomposition. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.