Description

(4As)-4,4A,5,6,8A,9-Hexahydro-3,8Aβ-Dimethyl-5-Methylenenaphtho[2,3-B]Furan CAS NO 2221-88-7 is a specialized, high-purity sesquiterpene lactone derivative with a complex fused-ring structure. This compound is valued for its unique chemical scaffold, which serves as a critical intermediate in advanced organic synthesis and pharmaceutical research. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting anti-inflammatory or anti-cancer pathways.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its complex terpenoid backbone for bioactivity.
• Fine Chemical Synthesis: Serves as a chiral starting material or advanced intermediate for synthesizing complex natural product analogs and specialty chemicals.
• Academic & R&D: Employed in university and institutional laboratories for methodological studies in organic chemistry and catalysis.
• Flavor & Fragrance Precursor: Potential use in the controlled synthesis of high-value aroma chemicals due to its terpene-related structure.

Basic Information

Item	Details
Product Name	(4As)-4,4A,5,6,8A,9-Hexahydro-3,8Aβ-Dimethyl-5-Methylenenaphtho[2,3-B]Furan
CAS No.	2221-88-7
Molecular Formula	C15H18O
Molecular Weight	214.30 g/mol
Synonyms	4,4a,5,6,8a,9-Hexahydro-3,8aβ-dimethyl-5-methylenenaphtho[2,3-b]furan; 5-Methylene-4,4a,5,6,8a,9-hexahydro-3,8aβ-dimethylnaphtho[2,3-b]furan; Alantolactone isomer; Isoalantolactone (related compound); Helenin (crude mixture); (+)-Isoalantolactone; Elecampane camphor constituent; Sesquiterpene lactone derivative.
EINECS	Contact for details

Quality Control

Every batch of (4As)-4,4A,5,6,8A,9-Hexahydro-3,8Aβ-Dimethyl-5-Methylenenaphtho[2,3-B]Furan is produced and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency meet the high standards required for research and industrial use. Certificates of Analysis (COA) documenting all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.