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(3As)-3A,4,5,5A,6,7,8,9,9Aβ,9Bα-Decahydro-5Aα-Methyl-3,9-Bis(Methylene)Naphtho[1,2-B]Furan-2(3H)-One CAS NO 2221-82-1
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CAS No.:2221-82-1
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
(3As)-3A,4,5,5A,6,7,8,9,9Aβ,9Bα-Decahydro-5Aα-Methyl-3,9-Bis(Methylene)Naphtho[1,2-B]Furan-2(3H)-One is a high-purity, complex sesquiterpene lactone derivative with a unique fused ring structure. This compound is valued for its role as a critical synthetic intermediate and building block in advanced organic synthesis. It is primarily sought after by research and development teams in the pharmaceutical and fine chemical industries for the development of novel active ingredients and specialty materials.
Application
- Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in oncology and anti-inflammatory research.
- Fine Chemical Synthesis: Used as a sophisticated building block for constructing complex natural product analogs and specialty organic molecules.
- Academic & Industrial R&D: Essential for methodological studies in organic chemistry, including cyclization and functionalization reactions.
- Agrochemical Research: Investigated as an intermediate for developing new crop protection agents with unique modes of action.
- Material Science: Potential starting material for synthesizing specialized polymers or ligands with specific stereochemical properties.
Basic Information
| Product Name | (3As)-3A,4,5,5A,6,7,8,9,9Aβ,9Bα-Decahydro-5Aα-Methyl-3,9-Bis(Methylene)Naphtho[1,2-B]Furan-2(3H)-One |
| CAS No. | 2221-82-1 |
| Molecular Formula | C16H20O2 |
| Molecular Weight | 244.33 g/mol |
| Synonyms | 5aα-Methyl-3,9-bis(methylene)-2,3,3a,4,5,5a,6,7,8,9,9aβ,9bα-dodecahydronaphtho[1,2-b]furan-2-one; 3,9-Bis(methylene)-5aα-methylperhydronaphtho[1,2-b]furan-2-one; Parthenolide analog; Parthenolide derivative; Sesquiterpene lactone intermediate; NSC 106977; (3aS,5aR,9aS,9bR)-5a-Methyl-3,9-bis(methylene)-2,3,3a,4,5,5a,6,7,8,9,9a,9b-dodecahydronaphtho[1,2-b]furan-2-one |
| EINECS | Contact for details |
Quality Control
Every batch of (3As)-3A,4,5,5A,6,7,8,9,9Aβ,9Bα-Decahydro-5Aα-Methyl-3,9-Bis(Methylene)Naphtho[1,2-B]Furan-2(3H)-One is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider inert gas purging to maintain stability.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to reference spectrum |
| Identification (HPLC) | Retention time matches reference standard |
| Assay (HPLC) | ≥ 97.0% |
| Related Substances (HPLC) | Total impurities ≤ 3.0% Any single impurity ≤ 1.0% |
| Residual Solvents (GC) | Meets ICH Q3C guidelines |
| Loss on Drying | ≤ 0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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