Description

Cyclocostunolide is a high-purity sesquiterpene lactone compound, valued for its role as a key intermediate and reference standard in advanced chemical synthesis and life science research. Its significance lies in its structural framework, which is foundational for developing novel pharmaceutical agents and bioactive molecules. This product is essential for research institutions, pharmaceutical developers, and fine chemical manufacturers focused on anti-inflammatory, anticancer, and other therapeutic applications.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly those targeting inflammatory pathways.
• Biochemical Research: Used as a reference standard and active probe in pharmacological and biological studies to investigate mechanisms of action.
• Natural Product Synthesis: A key starting material for the semi-synthesis of complex natural products and their analogs in medicinal chemistry.
• Cosmeceutical Development: Explored for potential application in high-end skincare formulations targeting specific cellular responses.
• Analytical Standard: Provides a certified reference material for quality control and analytical method development in laboratories.

Basic Information

Product Name	Cyclocostunolide
CAS No.	2221-81-0
Molecular Formula	C15H20O2
Molecular Weight	232.32 g/mol
Synonyms	Cyclocostunolide; 8α-Acetoxy-4,5-epoxy-6βH,7αH,11βH-germacr-1(10)-en-6,12-olide; Costunolide epoxide; 4,5-Epoxycostunolide; (+)-Cyclocostunolide; 2221-81-0; Germacranolide sesquiterpene
EINECS	Contact for details

Quality Control

Our Cyclocostunolide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to light and tendency for oxidation, it is recommended to handle under an inert atmosphere for long-term storage and to minimize headspace in opened containers.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.