Description

Menadiol Monoacetate is a synthetic, fat-soluble vitamin K derivative, serving as a key intermediate and active pharmaceutical ingredient. This compound is crucial for its role in supporting blood coagulation and bone metabolism, offering a stable and bioavailable form of vitamin K activity. It is primarily required by manufacturers in the pharmaceutical, nutraceutical, and animal feed industries for formulating supplements and therapeutic agents.

Application

• Pharmaceutical Synthesis: A vital intermediate in the production of various vitamin K analogs and active pharmaceutical ingredients (APIs).
• Dietary Supplements: Used as a source of vitamin K activity in multivitamin and specialized nutritional formulations.
• Animal Nutrition: Incorporated into premixes and feed additives to prevent vitamin K deficiency and support livestock health.
• Research & Development: Serves as a standard and reagent in biochemical research related to coagulation factors and bone studies.
• Cosmeceuticals: Explored for potential applications in topical formulations aimed at skin health and reducing the appearance of dark circles.

Basic Information

Product Name	Menadiol Monoacetate
CAS No.	2211-27-0
Molecular Formula	C13H12O3
Molecular Weight	216.23 g/mol
Synonyms	Vitamin K4 Monoacetate; Menadiol Acetate; 2-Methyl-1,4-naphthalenediol Monoacetate; 2-Methyl-1,4-naphthohydroquinone Monoacetate; 1,4-Dihydroxy-2-methylnaphthalene Monoacetate; Acetomenadione; Menadiol 1-Acetate; Kavitine
EINECS	218-655-9

Quality Control

Our Menadiol Monoacetate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with key parameters including assay, related substances, and residual solvents, supporting compliance with cGMP and relevant pharmacopeial guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.