Description

6-Bromo-2-oxo-2H-chromene-3-carbonyl chloride is a versatile and highly reactive organic intermediate, specifically a functionalized coumarin derivative. Its core value lies in its dual functionality, serving as a crucial building block for synthesizing more complex molecules in pharmaceutical and agrochemical research. This compound is primarily needed by R&D chemists and process development scientists working on novel active ingredients. Its reactive acid chloride group enables efficient amide bond formation, making it indispensable for creating targeted libraries of bioactive compounds.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in oncology and anti-inflammatory research.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides with enhanced efficacy.
• Fluorescent Probe & Dye Precursor: Serves as a starting material for synthesizing coumarin-based fluorescent tags and optical brighteners.
• Material Science Research: Employed in the synthesis of organic electronic materials and photoresponsive polymers.
• Academic & Contract Research: Essential for medicinal chemistry programs and structure-activity relationship (SAR) studies in university and CRO laboratories.
• Peptidomimetic Chemistry: Facilitates the incorporation of the coumarin scaffold into peptide-like structures for biochemical applications.

Basic Information

Product Name	6-Bromo-2-oxo-2H-chromene-3-carbonyl chloride
CAS No.	2199-94-2
Molecular Formula	C11H4BrClO3
Molecular Weight	299.50 g/mol
Synonyms	6-Bromocoumarin-3-carbonyl chloride; 6-Bromo-2-oxo-2H-1-benzopyran-3-carbonyl chloride; 3-Chlorocarbonyl-6-bromocoumarin; 6-Bromo-3-chlorocarbonylcoumarin; 6-Bromo-2H-chromen-2-one-3-carbonyl chloride; 6-Bromo-2-oxochromene-3-carbonyl chloride; 6-Bromo-2-oxo-2H-1-benzopyran-3-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 6-Bromo-2-oxo-2H-chromene-3-carbonyl chloride is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.