Description

Trichothecolone is a naturally occurring sesquiterpenoid mycotoxin belonging to the trichothecene family. This compound is of significant interest in biochemical and pharmaceutical research due to its potent biological activity and role as a key structural analog for studying toxin mechanisms. It serves as a critical reference standard and intermediate for researchers and manufacturers in the life sciences sector, particularly those focused on mycotoxicology, antifungal agent development, and metabolic pathway analysis.

Application

• Pharmaceutical Reference Standard: Serves as a high-purity certified standard for the qualitative and quantitative analysis of trichothecene mycotoxins in drug safety testing and regulatory compliance.
• Biochemical Research: Used as a key reagent in studying the biosynthesis, mode of action, and cellular toxicity of trichothecene compounds.
• Mycotoxin Analysis: Essential for calibrating analytical equipment (HPLC, LC-MS) and developing methods for the detection of trichothecenes in agricultural products, food, and feed.
• Antifungal Agent Development: Acts as a structural template or intermediate in the research and synthesis of novel antifungal and chemotherapeutic agents.
• Toxicology Studies: Employed in in-vitro and in-vivo studies to understand the toxicological impact and establish safety thresholds for trichothecene exposure.

Basic Information

Product Name	Trichothecolone
CAS No.	2199-06-6
Molecular Formula	C15H20O4
Molecular Weight	264.32 g/mol
Synonyms	4β-Hydroxy-12,13-epoxytrichothec-9-en-8-one; 12,13-Epoxytrichothec-9-en-4β-ol-8-one; NSC 163036; Trichothecin alcohol; Trichothecolone (8-oxotrichothecolone); Trichothec-9-ene-4β,12,13-triol-8-one; 4β-Hydroxy-12,13-epoxytrichothec-9-en-8-one
EINECS	Contact for details

Quality Control

Our Trichothecolone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Custom purity grades and analytical packages are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.