Description

5-Demethylnobiletin is a polymethoxyflavone derivative, a key bioactive compound found in citrus peels. This high-purity reference standard is essential for research and development in the nutraceutical and pharmaceutical sectors, where precise chemical characterization is critical. It is primarily sought by manufacturers and researchers focused on developing advanced health supplements, functional food ingredients, and novel therapeutic agents targeting metabolic and inflammatory pathways.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control in drug discovery and manufacturing.
• Nutraceutical & Dietary Supplement Formulation: Incorporated as a key active ingredient in supplements targeting cellular health, antioxidant support, and metabolic function.
• Biochemical & Pharmacological Research: Serves as a critical tool for in vitro and in vivo studies investigating mechanisms of action related to its bioactivity.
• Functional Food & Beverage Enhancement: Used to fortify products with scientifically-backed bioactive compounds for health-conscious consumers.
• Cosmeceutical Development: Applied in advanced skincare formulations for its potential antioxidant and anti-inflammatory properties.

Basic Information

Product Name	5-Demethylnobiletin
CAS No.	2174-59-6
Molecular Formula	C₂₀H₂₀O₇
Molecular Weight	372.37 g/mol
Synonyms	5-Hydroxy-6,7,8,3',4'-pentamethoxyflavone; 5-Demethylnobiletin; 5-Hydroxynobiletin; 6,7,8,3',4'-Pentamethoxy-5-hydroxyflavone; Nobletin D; Citrus Flavonoid 5-DMN
EINECS	Contact for details

Quality Control

Our 5-Demethylnobiletin is produced under strict quality management protocols. Each batch is subjected to comprehensive analytical testing, including HPLC for purity verification and identity confirmation via spectroscopic methods (IR, NMR). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Our commitment to quality supports your regulatory and research integrity requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.