Description

Clofazimine CAS NO 2030-63-9 is a riminophenazine antibiotic compound with a distinctive reddish-brown color. It is valued for its potent antimicrobial and anti-inflammatory properties, making it a critical agent in specific therapeutic areas. This product is primarily required by pharmaceutical manufacturers and research institutions developing treatments for mycobacterial infections and investigating novel therapeutic applications.

Application

• Pharmaceutical Active Ingredient (API): Primary use in the formulation of medications for the treatment of leprosy (Hansen's disease), particularly in multidrug therapy (MDT) regimens.
• Drug-Resistant Tuberculosis (TB) Therapy: An important component in combination therapies for the management of multidrug-resistant (MDR-TB) and extensively drug-resistant tuberculosis (XDR-TB).
• Anti-inflammatory Applications: Utilized in research and treatment for its immunomodulatory effects in conditions like psoriasis, lupus, and other autoimmune disorders.
• Antimicrobial Research: Serves as a reference standard and active compound in microbiological research against various Gram-positive bacteria and mycobacteria.
• Veterinary Pharmaceuticals: Investigated for use in treating mycobacterial infections in animals.
• Chemical Intermediate: Used in the synthesis of more complex riminophenazine derivatives for pharmacological screening.

Basic Information

Product Name	Clofazimine
CAS No.	2030-63-9
Molecular Formula	C27H22Cl2N4
Molecular Weight	473.40 g/mol
Synonyms	Lamprene; B-663; N,5-Bis(4-chlorophenyl)-3-(1-methylethyl)-3,5-dihydro-2H-phenazin-2-imine; G-30320; NSC-141046; 3-(p-Chloroanilino)-10-(p-chlorophenyl)-2,10-dihydro-2-(isopropylimino)phenazine; Clofaziminum; Clofazimina
EINECS	217-984-6

Quality Control

Our Clofazimine is manufactured under strict quality systems to ensure it meets the stringent requirements for pharmaceutical intermediates and active ingredients. Quality is verified through comprehensive analytical testing, including HPLC for purity, identification by IR and UV-Vis spectroscopy, and control of related substances. While we offer material suitable for research and GMP manufacturing, Certificates of Analysis (COA) are provided with each batch, detailing compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	Reddish-brown to orange-brown crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity: ≤ 0.5%; Total impurities: ≤ 1.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.