Description

(+)-Bulbocapnine CAS NO 298-45-3 is a naturally occurring isoquinoline alkaloid of significant interest in biochemical and pharmacological research. This compound serves as a valuable reference standard and a key intermediate in the synthesis of more complex molecules. It is primarily utilized by research institutions and pharmaceutical development companies engaged in neuroscience and neuropharmacology studies.

Application

• Pharmacological Research: Used as a reference standard in studies investigating dopamine receptor antagonism and its effects on motor function.
• Neuroscience Studies: Employed in research models to study catalepsy and other neurological phenomena.
• Biochemical Assay Development: Serves as a critical component in developing and validating assays for enzyme inhibition studies.
• Pharmaceutical Intermediates: Acts as a key chiral building block in the synthetic pathways for more complex bioactive molecules.
• Reference Material: Provides a high-purity standard for quality control in the production of related alkaloids and for analytical method calibration.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic chemistry and medicinal chemistry.

Basic Information

Product Name	(+)-Bulbocapnine
CAS No.	298-45-3
Molecular Formula	C19H19NO4
Molecular Weight	325.36 g/mol
Synonyms	(+)-Bulbocapnine; (6aS)-5,6,6a,7-Tetrahydro-1,2,9,10-tetramethoxy-6-methyl-4H-dibenzo[de,g]quinoline; Bulbocapnine; L-Bulbocapnine; NSC 15381; Bulbokapnin; Bulbocapnina; Bulbocapninum
EINECS	206-064-5

Quality Control

Our (+)-Bulbocapnine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Optical Rotation	[α]20/D +62° to +66° (c=1 in CHCl3)
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.