Description

(2R,2'R,3R,3'R)-3,3'-Bis(tert-Butyl)-2,2',3,3'-Tetrahydro-4,4'-Bis(Phenylmethoxy)-2,2'-Bi-1,3-Benzoxaphosphole CAS NO 1994323-92-0 is a high-purity, chiral organophosphorus compound characterized by its unique binaphthol-derived backbone. This compound matters as a sophisticated ligand or catalyst precursor in asymmetric synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel chiral molecules.

Application

• Asymmetric Catalysis: Serving as a chiral ligand for transition metal-catalyzed reactions, including hydrogenation, cross-coupling, and C-H activation.
• Pharmaceutical Intermediate Synthesis: A key building block or catalyst in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs).
• Agrochemical Development: Used in the research and production of chiral pesticides and herbicides for enhanced efficacy and environmental safety.
• Material Science Research: Potential application in the development of chiral polymers, liquid crystals, or sensors.
• Academic & Industrial R&D: A valuable tool for methodological development in organic and organometallic chemistry laboratories.

Basic Information

Product Name	(2R,2'R,3R,3'R)-3,3'-Bis(tert-Butyl)-2,2',3,3'-Tetrahydro-4,4'-Bis(Phenylmethoxy)-2,2'-Bi-1,3-Benzoxaphosphole
CAS No.	1994323-92-0
Molecular Formula	C42H44O4P2
Molecular Weight	674.73 g/mol
Synonyms	3,3'-Di-tert-butyl-4,4'-bis(benzyloxy)-2,2',3,3'-tetrahydro-2,2'-bi-1,3-benzoxaphosphole; (R,R)-3,3'-Bis(tert-butyl)-4,4'-bis(benzyloxy)-2,2',3,3'-tetrahydro-2,2'-bi-1,3-benzoxaphosphole; BIBOP-Benzyl Ligand; Chiral Binaphthol-Based Phosphite; (R)-DTB-BIBOP(Bn); DTBBIBOP(Bn); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our (2R,2'R,3R,3'R)-3,3'-Bis(tert-Butyl)-2,2',3,3'-Tetrahydro-4,4'-Bis(Phenylmethoxy)-2,2'-Bi-1,3-Benzoxaphosphole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) and NMR for structural confirmation, to ensure high chemical and optical purity. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.