Description

tert-Butyl(S)-6-Methyl-6,7-Dihydropyrazolo[1,5-A]Pyrazine-5(4H)-Carboxylate is a high-purity chiral building block and advanced pharmaceutical intermediate. This compound is of significant value for its role in constructing complex nitrogen-containing heterocycles, which are core scaffolds in modern drug discovery. It is primarily needed by research institutions and pharmaceutical companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for therapeutic areas like oncology and central nervous system (CNS) disorders.

Application

• Key Intermediate in API Synthesis: Serves as a critical chiral precursor in the multi-step synthesis of complex drug candidates.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Asymmetric Synthesis: Employed in the development of stereoselective synthetic routes due to its defined (S)-configuration.
• Process Chemistry Development: Utilized for scaling up synthetic pathways from laboratory to pilot plant and commercial manufacturing scales.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Library Synthesis: Used to generate focused chemical libraries for high-throughput screening against biological targets.

Basic Information

Item	Details
Product Name	tert-Butyl(S)-6-Methyl-6,7-Dihydropyrazolo[1,5-A]Pyrazine-5(4H)-Carboxylate
CAS No.	1967003-62-8
Molecular Formula	C13H19N3O2
Molecular Weight	249.31 g/mol
Synonyms	(S)-tert-Butyl 6-methyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-5-carboxylate; (S)-5-(tert-Butoxycarbonyl)-6-methyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine; tert-Butyl (6S)-6-methyl-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-5-carboxylate; (S)-6-Methyl-5-Boc-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine; (S)-5-Boc-6-methyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine; (S)-Boc-6-methyl-DHP; Chiral Pyrazolopyrazine Building Block
EINECS	Contact for details

Quality Control

Our tert-Butyl(S)-6-Methyl-6,7-Dihydropyrazolo[1,5-A]Pyrazine-5(4H)-Carboxylate is manufactured under strict quality systems suitable for pharmaceutical R&D. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure high chemical and enantiomeric purity. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) are provided and available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.