Description

Carbamic Acid,n-[trans-4-(1-Piperazinyl)Cyclohexyl]-, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is valued for its role as a critical building block in medicinal chemistry, enabling the development of targeted therapeutics. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel drug candidates, particularly in areas requiring sophisticated nitrogen-containing heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Serves as a versatile building block for constructing complex molecular architectures in drug discovery and lead optimization programs.
• API Synthesis: Used in the production of active pharmaceutical ingredients (APIs) that incorporate a trans-cyclohexylpiperazine moiety.
• Chemical Reference Standard: Employed as a high-purity standard for analytical method development, validation, and quality control in pharmaceutical laboratories.
• Process Development: Utilized in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, non-commercial chemical entities for clinical trials.

Basic Information

Product Name	Carbamic Acid,n-[trans-4-(1-Piperazinyl)Cyclohexyl]-, 1,1-Dimethylethyl Ester
CAS No.	1956370-76-5
Molecular Formula	C15H29N3O2
Molecular Weight	283.41 g/mol
Synonyms	tert-Butyl N-[trans-4-(piperazin-1-yl)cyclohexyl]carbamate; trans-4-(1-Boc-piperazin-4-yl)cyclohexylamine derivative; trans-N-Boc-4-(piperazin-1-yl)cyclohexanamine; 1,1-Dimethylethyl N-[4-(1-piperazinyl)cyclohexyl]carbamate (trans); trans-4-(Piperazin-1-yl)cyclohexylcarbamic acid tert-butyl ester; Boc-trans-4-(piperazin-1-yl)cyclohexylamine; UNII-Contact for details
EINECS	Contact for details

Quality Control

Our Carbamic Acid,n-[trans-4-(1-Piperazinyl)Cyclohexyl]-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring the material is suitable for use in advanced pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; therefore, containers should be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.