Description

3-Chloro-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride is a high-purity, heterocyclic organic compound that serves as a critical building block in modern pharmaceutical research and development. Its value lies in its unique fused triazolopyrazine structure, which is highly sought after for creating novel bioactive molecules. This intermediate is primarily needed by research institutions and pharmaceutical companies engaged in the synthesis of new drug candidates, particularly for central nervous system (CNS) and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used extensively in hit-to-lead and lead optimization campaigns for structure-activity relationship (SAR) studies.
• Library Synthesis: A valuable scaffold for constructing diverse compound libraries for high-throughput screening.
• CNS Drug Discovery: The triazolopyrazine core is frequently explored in the synthesis of potential neuroactive compounds.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes to study biological pathways.
• Process Chemistry: Serves as a starting material for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.

Basic Information

Product Name	3-Chloro-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride
CAS No.	1956369-87-1
Molecular Formula	C6H9Cl2N4
Molecular Weight	208.07 g/mol
Synonyms	3-Chloro-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyrazine HCl; 3-Chloro-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyrazine hydrochloride; 1,2,4-Triazolo[4,3-a]pyrazine, 3-chloro-5,6,7,8-tetrahydro-, hydrochloride (1:1); 3-Chloro-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine monohydrochloride
EINECS	Contact for details

Quality Control

Our 3-Chloro-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. Certificates of Analysis (COA) are available for every batch and supplied upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.