Description

1-(Trifluormethyl)Piperazinhydrochlorid (1:1) is a high-purity, functionalized piperazine derivative used as a key building block in advanced organic synthesis. This compound is valued for its role in introducing the trifluoromethyl-piperazine moiety, a privileged scaffold known to enhance the metabolic stability and binding affinity of target molecules. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients. The material is supplied as a CAS NO 1956321-71-3 registered compound, ensuring precise identification and traceability.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology drug candidates.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the trifluoromethyl group improves lipophilicity and biological activity.
• Chemical Biology & Medicinal Chemistry: Serves as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Material Science: Potential monomer or modifier in the synthesis of specialty polymers and advanced materials with unique surface properties.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations engaged in custom synthesis and process development for client projects.

Basic Information

Product Name	1-(Trifluormethyl)Piperazinhydrochlorid (1:1)
CAS No.	1956321-71-3
Molecular Formula	C5H10ClF3N2
Molecular Weight	190.59 g/mol
Synonyms	1-(Trifluoromethyl)piperazine hydrochloride; 1-(Trifluoromethyl)piperazine HCl; 1-Trifluoromethylpiperazine hydrochloride; Piperazine, 1-(trifluoromethyl)-, hydrochloride (1:1); 1-Trifluoromethyl-piperazine hydrochloride; 1-Piperazinecarboxylic acid, 4-(trifluoromethyl)-, hydrochloride; Trifluoromethylpiperazine HCl; TFMP hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(Trifluormethyl)Piperazinhydrochlorid (1:1) is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) providing batch-specific results is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator or inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.