Description

cis-4-Methyl-3-(Trifluoromethyl)Piperidin-3-Ol Hydrochloride (Wx601583) is a high-purity, advanced pharmaceutical intermediate featuring a unique trifluoromethylated piperidine scaffold. This compound is critical for medicinal chemistry research and development, offering a versatile building block for the synthesis of novel bioactive molecules. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers focused on developing new drug candidates, particularly in the areas of central nervous system (CNS) and metabolic disease therapeutics.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of potential active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug discovery programs.
• Protease Inhibitor Development: The piperidine-ol structure is valuable for creating inhibitors targeting various enzymes.
• Agrochemical Synthesis: Serves as a precursor for developing advanced crop protection agents with improved efficacy.
• Ligand and Catalyst Development: Utilized in the preparation of chiral ligands for asymmetric catalysis.
• Chemical Biology Probes: Acts as a core structure for developing molecular probes to study biological pathways.

Basic Information

Item	Details
Product Name	cis-4-Methyl-3-(Trifluoromethyl)Piperidin-3-Ol Hydrochloride (Wx601583)
CAS No.	1951444-38-4
Molecular Formula	C8H15ClF3NO
Molecular Weight	233.66 g/mol
Synonyms	cis-4-Methyl-3-(trifluoromethyl)piperidin-3-ol hydrochloride; 3-Piperidinol, 4-methyl-3-(trifluoromethyl)-, hydrochloride, cis-; (3R,4S)-4-Methyl-3-(trifluoromethyl)piperidin-3-ol hydrochloride; (3S,4R)-4-Methyl-3-(trifluoromethyl)piperidin-3-ol hydrochloride; WX-601583; Wx601583; 1951444-38-4; 4-Methyl-3-(trifluoromethyl)piperidin-3-ol HCl
EINECS	Contact for details

Quality Control

Our cis-4-Methyl-3-(Trifluoromethyl)Piperidin-3-Ol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.