Description

Benzyl (5,5-Difluoropiperidin-3-Yl)Carbamate Hydrochloride (Wx601248) is a high-purity, fluorinated piperidine derivative and a key pharmaceutical intermediate. This compound matters for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting neurological and metabolic disorders. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the development of new drug candidates.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, especially those targeting protease or kinase enzymes.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Process Chemistry Development: Serves as a starting material or advanced intermediate in scaling up synthetic routes for Active Pharmaceutical Ingredients (APIs).
• Bioconjugation & Probe Synthesis: The carbamate and amine functionalities make it suitable for creating chemical probes or conjugates for biological studies.
• Library Synthesis for High-Throughput Screening: Employed in the generation of diverse compound libraries for drug discovery screening campaigns.

Basic Information

Product Name	Benzyl (5,5-Difluoropiperidin-3-Yl)Carbamate Hydrochloride (Wx601248)
CAS No.	1951441-61-4
Molecular Formula	C13H17ClF2N2O2
Molecular Weight	306.74 g/mol
Synonyms	Benzyl N-(5,5-difluoropiperidin-3-yl)carbamate hydrochloride; 3-(((Benzyloxy)carbonyl)amino)-5,5-difluoropiperidine hydrochloride; Carbamic acid, N-(5,5-difluoropiperidin-3-yl)-, benzyl ester, hydrochloride; WX-601248; Wx601248
EINECS	Contact for details

Quality Control

Our Benzyl (5,5-Difluoropiperidin-3-Yl)Carbamate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.