Description

trans-Benzyl 5-Amino-2-Methylpiperidine-1-Carboxylate Hydrochloride (Wx601408) is a high-purity, protected piperidine derivative used as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and other therapeutic areas.
• Peptidomimetic Chemistry: Used to introduce constrained, substituted piperidine scaffolds into peptide backbones to modulate biological activity and stability.
• Agrochemical Synthesis: Serves as a precursor in the development of novel pesticides and herbicides requiring specific stereochemistry.
• Ligand and Catalyst Development: Employed in the synthesis of chiral ligands and organocatalysts for asymmetric synthesis.
• Chemical Biology Probes: Useful for creating tool compounds and probes to study biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A starting material for custom synthesis projects requiring high-purity, complex heterocyclic intermediates.

Basic Information

Product Name	trans-Benzyl 5-Amino-2-Methylpiperidine-1-Carboxylate Hydrochloride (Wx601408)
CAS No.	1951439-14-7
Molecular Formula	C15H23ClN2O2
Molecular Weight	298.81 g/mol
Synonyms	1-[(Benzyloxy)carbonyl]-5-amino-2-methylpiperidine hydrochloride (trans); Benzyl (2R,5S)-5-Amino-2-methylpiperidine-1-carboxylate Hydrochloride; Benzyl 5-Amino-2-methylpiperidine-1-carboxylate HCl (trans); WX-601408; 1-CBz-5-Amino-2-methylpiperidine hydrochloride; trans-1-N-CBz-5-Amino-2-methylpiperidine HCl; (2R,5S)-1-[(Benzyloxy)carbonyl]-5-amino-2-methylpiperidinium chloride
EINECS	Contact for details

Quality Control

Our trans-Benzyl 5-Amino-2-Methylpiperidine-1-Carboxylate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for stereochemical integrity, and identity confirmation via IR and NMR. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.