Description

n-Methyl-n-((Z)-4-(2-(5-((5R)-3-Oxooctahydro-1H-Cyclopenta[B]Pyrazin-5-Yl)Pentanoyl)Hydrazono) is a high-purity, advanced pharmaceutical intermediate with a complex, stereochemically defined structure. This compound is critical for the synthesis of novel therapeutic agents, particularly in the development of targeted small-molecule drugs. It is primarily required by pharmaceutical R&D laboratories and contract manufacturing organizations (CMOs) working in oncology, metabolic disorders, and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs) with cyclopenta[b]pyrazinone scaffolds.
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization programs.
• Preclinical Development: Serves as a critical material for producing batches of candidate drugs for pharmacological and toxicological testing.
• Process Chemistry: Employed in route scouting and scale-up studies for the development of efficient commercial manufacturing processes.
• Proteolysis-Targeting Chimera (PROTAC) Development: Potential use as a component in the design of bifunctional molecules for targeted protein degradation.
• Chemical Biology Probes: Utilized to create tool compounds for investigating specific biological pathways and target validation.

Basic Information

Item	Detail
Product Name	n-Methyl-n-((Z)-4-(2-(5-((5R)-3-Oxooctahydro-1H-Cyclopenta[B]Pyrazin-5-Yl)Pentanoyl)Hydrazono)
CAS No.	1951430-53-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	5-[(5R)-3-Oxooctahydro-1H-cyclopenta[b]pyrazin-5-yl]-N'-[(1Z)-1-(methylamino)-4-oxopent-1-en-2-yl]pentanehydrazide; (5R)-5-[5-[(Z)-2-[Methyl(4-oxopentanoyl)hydrazono]ethyl]pentyl]octahydro-1H-cyclopenta[b]pyrazin-3-one; CAS 1951430-53-7; n-Methyl-n-((Z)-4-(2-(5-((5R)-3-Oxooctahydro-1H-Cyclopenta[B]Pyrazin-5-Yl)Pentanoyl)Hydrazinylidene); Advanced Cyclopentapyrazinone Intermediate; Methyl-hydrazono Pentanoyl Cyclopenta Pyrazin Derivative.
EINECS	Contact for details

Quality Control

This product is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Quality is verified through advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support regulatory filings and internal quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to prevent oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area, separate from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.