Description

3-Bromo-6-Chloro-1H-Pyrazolo[3,4-B]Pyrazine is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique fused bicyclic structure, which serves as a versatile scaffold for constructing complex molecules with tailored biological and material properties. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used as a core scaffold for developing novel herbicides, fungicides, and insecticides with new modes of action.
• Material Science: Serves as a building block for creating organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways.
• Custom Synthesis: An essential starting material for contract research and manufacturing organizations (CROs/CMOs) engaged in custom and scale-up synthesis projects.

Basic Information

Product Name	3-Bromo-6-Chloro-1H-Pyrazolo[3,4-B]Pyrazine
CAS No.	1936225-21-6
Molecular Formula	C5H2BrClN4
Molecular Weight	233.45 g/mol
Synonyms	3-Bromo-6-chloro-1H-pyrazolo[3,4-b]pyrazine; 1H-Pyrazolo[3,4-b]pyrazine, 3-bromo-6-chloro-; 3-Bromo-6-chloro-1H-pyrazolo[3,4-b]pyrazine; 1936225-21-6; 3-Br-6-Cl-1H-pyrazolo[3,4-b]pyrazine; Bromo-chloro-pyrazolopyrazine; Pyrazolo[3,4-b]pyrazine, bromo-chloro derivative
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-6-Chloro-1H-Pyrazolo[3,4-B]Pyrazine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency, meeting the stringent requirements of research and pre-clinical development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95% (Standard Grade)
Purity (HPLC)	≥ 98% (High Purity Grade)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.