Description

2-Pyrazinamine, 6-Chloro-3-Ethynyl- is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its unique molecular architecture, which combines a halogenated pyrazine core with a reactive ethynyl group, enabling precise molecular construction. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science Research: Acts as a precursor for functionalized polymers or metal-organic frameworks (MOFs) due to its ethynyl group, which can participate in click chemistry reactions.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Product Name	2-Pyrazinamine, 6-Chloro-3-Ethynyl-
CAS No.	1936114-56-5
Molecular Formula	C6H4ClN3
Molecular Weight	153.57 g/mol
Synonyms	6-Chloro-3-ethynylpyrazin-2-amine; 3-Ethynyl-6-chloropyrazin-2-amine; 6-Chloro-3-ethynyl-2-pyrazinamine; 2-Amino-6-chloro-3-ethynylpyrazine; 6-Chloro-3-ethynyl-2-aminopyrazine; 1936114-56-5; 6-Chloro-3-ethynylpyrazine-2-amine
EINECS	Contact for details

Quality Control

Our 2-Pyrazinamine, 6-Chloro-3-Ethynyl- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.