Description

1-Piperidinecarboxylic Acid, 3-Amino-4-Hydroxy-, Phenylmethyl Ester, (3S,4S)- is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex pharmacophores, particularly in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. Pharmaceutical researchers and process chemists need this material for its precise stereochemistry and functional groups, which are critical for synthesizing targeted molecules with high enantiomeric purity.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and cardiovascular targets.
• Peptidomimetic Synthesis: Used to incorporate constrained amino acid analogs into peptide chains to enhance stability and biological activity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing sophisticated chiral ligands and organocatalysts.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals for agrochemical and material science applications.
• Academic & Contract Research: Essential for medicinal chemistry programs and process optimization studies in academic and industrial R&D laboratories.

Basic Information

Product Name	1-Piperidinecarboxylic Acid, 3-Amino-4-Hydroxy-, Phenylmethyl Ester, (3S,4S)-
CAS No.	1932598-12-3
Molecular Formula	C13H18N2O3
Molecular Weight	250.29 g/mol
Synonyms	(3S,4S)-3-Amino-4-hydroxypiperidine-1-carboxylic acid benzyl ester; Benzyl (3S,4S)-3-amino-4-hydroxypiperidine-1-carboxylate; (3S,4S)-Benzyl 3-amino-4-hydroxypiperidine-1-carboxylate; 1-N-CBZ-3-amino-4-hydroxypiperidine, (3S,4S)-; (3S,4S)-1-Carbobenzyloxy-3-amino-4-hydroxypiperidine; (3S,4S)-3-Amino-4-hydroxy-1-[(phenylmethoxy)carbonyl]piperidine; (3S,4S)-AHPCP-CBZ
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency for critical R&D and scale-up work. Each lot is characterized using advanced analytical techniques including HPLC, chiral chromatography, and NMR to confirm identity, high chemical purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.