Description

tert-Butyl (2R,5S)-5-Ethyl-2-Methylpiperazine-1-Carboxylate is a high-purity, stereochemically defined piperazine derivative used as a critical chiral building block in advanced organic synthesis. Its value lies in providing a rigid, protected scaffold for constructing complex molecules with precise stereochemistry. This compound is essential for researchers and manufacturers in the pharmaceutical industry, particularly for developing active pharmaceutical ingredients (APIs) and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug molecules, particularly those targeting the central nervous system (CNS) and infectious diseases.
• API Development: Serves as a core structural component in the research and production of new Active Pharmaceutical Ingredients (APIs) requiring specific stereochemistry.
• Asymmetric Synthesis: Used as a ligand precursor or chiral auxiliary in catalytic asymmetric reactions to induce enantioselectivity.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization for novel drug candidates.
• Peptidomimetics: Acts as a constrained, non-natural amino acid surrogate in the design of peptide-like compounds with enhanced metabolic stability.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying biological pathways and target engagement.

Basic Information

Product Name	tert-Butyl (2R,5S)-5-Ethyl-2-Methylpiperazine-1-Carboxylate
CAS No.	1932513-31-9
Molecular Formula	C12H24N2O2
Molecular Weight	228.33 g/mol
Synonyms	1-Boc-(2R,5S)-5-Ethyl-2-methylpiperazine; (2R,5S)-1-(tert-Butoxycarbonyl)-5-ethyl-2-methylpiperazine; tert-Butyl (2R,5S)-5-ethyl-2-methylpiperazine-1-carboxylate; (2R,5S)-5-Ethyl-2-methylpiperazine-1-carboxylic acid tert-butyl ester; Boc-(2R,5S)-5-Ethyl-2-methylpiperazine; (2R,5S)-N-Boc-5-Ethyl-2-methylpiperazine; (2R,5S)-5-Ethyl-2-methyl-1-(tert-butoxycarbonyl)piperazine
EINECS	Contact for details

Quality Control

Our tert-Butyl (2R,5S)-5-Ethyl-2-Methylpiperazine-1-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including chiral HPLC to confirm stereochemical purity and identity. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.