Description

(R)-1-Methyl-6-Oxopiperidine-3-Carboxylic Acid CAS NO 1932309-72-2 is a high-purity chiral piperidine derivative serving as a critical building block in modern organic synthesis. Its value lies in providing a stereochemically defined scaffold essential for constructing complex molecules with specific biological activity. This intermediate is primarily needed by pharmaceutical and biotechnology research organizations engaged in the development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, especially for neurological and psychiatric applications.
• API Synthesis: Used in the construction of complex molecular architectures for potential drug candidates targeting G-protein-coupled receptors (GPCRs).
• Asymmetric Synthesis: Employed as a starting material or intermediate in catalytic asymmetric reactions to introduce stereogenic centers.
• Medicinal Chemistry Research: Serves as a versatile scaffold for creating focused libraries of compounds in structure-activity relationship (SAR) studies.
• Chemical Biology Probes: Utilized in the synthesis of labeled compounds or molecular probes for investigating biological pathways.
• Process Chemistry Development: Acts as a critical intermediate during the scale-up and optimization of synthetic routes for clinical trial material.

Basic Information

Product Name	(R)-1-Methyl-6-Oxopiperidine-3-Carboxylic Acid
CAS No.	1932309-72-2
Molecular Formula	C8H13NO3
Molecular Weight	171.19 g/mol
Synonyms	(3R)-1-Methyl-6-oxopiperidine-3-carboxylic acid; (R)-1-Methyl-6-oxo-3-piperidinecarboxylic acid; (R)-1-Methylpiperidine-6-one-3-carboxylic acid; 3-Piperidinecarboxylic acid, 1-methyl-6-oxo-, (3R)-; (R)-1-Methyl-6-oxo-1,2,3,6-tetrahydropyridine-3-carboxylic acid; (R)-1-Methyl-6-oxo-3-piperidinecarboxylate; (R)-1-Methyl-6-oxopiperidine-3-carboxylate
EINECS	Contact for details

Quality Control

Our (R)-1-Methyl-6-Oxopiperidine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with research and development grade standards. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere when appropriate to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.